Association of CYP19 polymorphisms with breast cancer risk: A case-control study
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولRisk Factors of Breast Cancer in Kuwait: Case-Control Study
Background: Breast cancer incidence has increased rapidly inKuwait, but there haven’t been any studies investigating the recognized risk factors of breast cancer inKuwait. The aim of the study was to investigate breast cancer risk factors among women inKuwait. Methods: A case-control study was conducted in Kuwait from May 2003 to March 2004 using a questionnaire including socio-demographic data...
متن کاملAssociation of common PALB2 polymorphisms with breast cancer risk: a case-control study.
PURPOSE The PALB2 gene has an essential role in BRCA2-mediated DNA double-strand break repair and intra-S phase DNA damage checkpoint control, and its mutations are moderately associated with breast cancer susceptibility. This study was designed to investigate the common variants of PALB2 and their association with breast cancer risk. EXPERIMENTAL DESIGN Four single nucleotide polymorphisms (...
متن کاملAssociation of CYP1A1*2 polymorphisms with breast cancer risk: a case control study.
BACKGROUND The Cytochrome P-4501A1 (CYP1A1) gene, located on chromosome 15q, is involved in the metabolism of carcinogens mainly polycyclic aromatic hydrocarbons as well as estrogen. It is considered as candidate gene for low-penetrance breast cancer susceptibility. Hence the present study aims to discuss the role of CYP1A1 polymorphisms in breast cancer. MATERIALS AND METHODS A total of 250 ...
متن کاملStudy of the association FokI polymorphisms of the XRCC3 gene with the risk of breast cancer in women: brief report
Background: Breast cancer is one of the most common worldwide malignancies among women. Biological data suggest that damage induced by endogenous and exogenous factors affects the integrity of DNA and associated with susceptibility to breast cancer. Single nucleotide polymorphisms (SNPs) in DNA repair genes can associated with differences in the repair efficiency of DNA damage and may affect br...
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ژورنال
عنوان ژورنال: Journal of Natural Science, Biology and Medicine
سال: 2014
ISSN: 0976-9668
DOI: 10.4103/0976-9668.136150